Original ArticlesEUS-guided FNA of the left adrenal gland in patients with thoracic or GI malignancies☆
Section snippets
Patients and methods
The study was approved by the respective institution review boards at both participating institutions. All patients with an enlarged adrenal gland on abdominal imaging (CT, magnetic resonance imaging [MRI], and/or positron emission tomography [PET]) (Fig. 1), with known or suspected malignancy referred to two centers with EUS expertise over a 3-year period (2000-2003) were included. Data were collected prospectively as an ongoing observational study of EUS-FNA at one center (University of
Results
Over the study period, 31 patients (21 men, 10 women; median age 65 years; range 48-85 years) underwent EUS-FNA of an enlarged left adrenal gland at the two centers. The majority (24/31; 77.4%) were white (Table 1). In one patient, CT-guided FNA before EUS-FNA was unsuccessful. In another patient, the mass was not amenable to CT-guided sampling, and this patient, therefore, was referred for EUS-FNA. Tissue adequate for interpretation was obtained in all patients; no EUS-FNA was unsuccessful.
Discussion
The detection of distant metastasis in patients with lung cancer has a major impact on prognosis and management.1 Studies have shown that in patients with non-small-cell lung cancer, an isolated adrenal mass is more likely to be an adenoma, and, thus, tissue diagnosis is required before a decision against potential curative resection is made.1., 18. In addition, it cannot be assumed that an isolated adrenal mass in a patient with non-small-cell bronchogenic carcinoma represents metastasis,
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These authors contributed equally to the manuscript