Endoscopic ultrasound–guided fine-needle aspiration biopsy using linear array and radial scanning endosonography☆,☆☆,★
Section snippets
Data retrieval
Information on all patients undergoing EUS with or without FNA have been prospectively entered into a database since 1993. Data regarding follow-up were included in this database and used to make a subjective determination as to whether the FNA result changed the management of each patient. Computer search for all attempted and successful FNA patients yielded this study subset.
Patient selection
All patients referred for EUS-guided FNA biopsy based on the results of previous imaging studies (usually endoscopy or
Results
Two hundred eight consecutive patients (119 men/89 women) underwent EUS-guided FNA procedures through December 1995. The mean age of this group was 61 years (range 16 to 87 years). A total of 208 lesions were targeted in 208 patients and a total of 705 FNA passes were performed for a mean of 3.39 passes per patient. In 26% (54 of 208) of patients, previous attempts at biopsy by other methods were unsuccessful.
One hundred twenty-one (58%) of the lesions sampled were pancreatic masses, 27 (13%)
Discussion
EUS-guided FNA was highly accurate for detecting mediastinal lymph node metastasis and diagnosing perirectal and pancreatic masses. We had an overall diagnostic accuracy of 87%. We began utilizing the radial scanning instrument for EUS-guided FNA during prolonged absence of the linear array instrument due to several perforations sustained during early prototype FNA needle development. Our initial experience involved mediastinal LN and progressed to pancreatic and submucosal lesions. Since the
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Cited by (0)
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From the Division of Gastroenterology and Hepatology, Indiana University Medical Center, Indianapolis, Indiana.
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Reprint requests: Frank Gress, MD, Gastroenterology and Hepatology, Indiana University Medical Center, 550 North University Blvd., Room 2300, Indianapolis, IN 46202.
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