Original contributionThe clinical significance of focal active colitis
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Is focal active colitis of greater clinical significance in pediatric patients? A retrospective review of 68 cases with clinical correlation
2018, Human PathologyCitation Excerpt :Approximately 20%–30% were thought to be idiopathic (likely the result of bowel preparation with sodium phosphate). Of the remainder, approximately 0% [1], 16% [3], and 13% [4] were thought to have underlying IBD, specifically CD. In the pediatric population there are likely to be fewer confounding factors that could cause FAC, including the recommendation that children do not receive oral sodium phosphate bowel preparations [5] and they are less likely to be taking non-steroidal anti-inflammatory drugs (NSAIDs), proton pump inhibitors (PPIs) and corticosteroids, all of which have been associated with colonic inflammation [6-12].
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