Research LettersSclerosing pancreato-cholangitis responsive to steroid therapy
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2013, Journal of HepatologyCitation Excerpt :We report three patients with HHT, for whom their predominant clinical presentation was with ischemic cholangiopathy. In these patients, anti-vascular endothelial growth factor therapy not only obviated the need for liver transplantation in the first year of follow-up, but also resolved biliary features sufficiently to be demonstrable radiologically, in a striking manner given that reversal of biliary disease is rarely reported [11]. Our report therefore provides helpful, albeit relatively short term, information of benefit to patients with HHT and biliary disease, as well as more broadly to investigators who seek to understand further mechanisms by which the biliary tree can be damaged by vascular insufficiency.
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