Editorial
The Early Diagnosis of Chronic Pancreatitis

https://doi.org/10.1016/j.cgh.2008.08.008Get rights and content

Cited by (35)

  • Biomarkers of Chronic Pancreatitis: A systematic literature review

    2021, Pancreatology
    Citation Excerpt :

    Current diagnostic methods for CP are highly accurate for moderate to advanced disease and include abdominal radiographic imaging [12], endoscopic procedures (EUS), and functional testing methods, including measurement of analytes in pancreas fluid after secretin or cholecystokinin stimulation [13–15]. However, none of these testing methods are suitable for early-stage CP diagnosis in isolation [16]. Often, a confident diagnosis of CP is not confirmed until end-stage clinical features are evident, indicating moderate to severe fibrotic changes of the pancreas gland [13,17–19].

  • Aryl Hydrocarbon Receptor Ligands in Cigarette Smoke Induce Production of Interleukin-22 to Promote Pancreatic Fibrosis in Models of Chronic Pancreatitis

    2016, Gastroenterology
    Citation Excerpt :

    Future prospective studies with large cohorts of patients will be necessary to address the significance of these observations. Early diagnosis of CP remains a major challenge in the field and chronic pancreatic inflammation and fibrosis develop in the apparent absence of symptoms or detectable clinical measures.42 Current imaging diagnostics, such as computed tomography scans and endoscopic ultrasounds, detect relatively late stages of the disease.

  • Chronic pancreatitis: From guidelines to clinical practice

    2012, Italian Journal of Medicine
    Citation Excerpt :

    Long-term outcome, pain, pancreatic failure, diabetes and risk of cancer were considered. Main references are [7–15]. Question: Are there different patterns of pain in CP?

  • Cytokine profiling of pancreatic fluid using the ePFT collection method in tandem with a multiplexed microarray assay

    2011, Journal of Immunological Methods
    Citation Excerpt :

    As determined from its electrolyte composition and enzyme activity, the ePFT-collected fluid reproduces the classic acinar and duct cell secretory profiles following hormonal stimulation (Conwell et al., 2002; Conwell et al., 2003a; Conwell et al., 2003b; Stevens et al., 2004a; Stevens et al., 2004b). The ePFT is now considered an acceptable alternative method for the assessment of pancreas secretory physiology (Pollack and Grendell, 2006; Forsmark, 2008). Furthermore, pancreatic fluid collected by the ePFT method is fully amenable to proteomic analysis (Paulo et al., 2011).

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