Original articleEffectiveness of laparoscopic sleeve gastrectomy on glycemic control in obese Indians with type 2 diabetes mellitus
Section snippets
Methods
The study was conducted at the Ruby Hall Medical Center, a tertiary care hospital located in Pune, India from January 2004 to September 2007. The institutional ethics committee approved this prospective study. The patients were screened for participating in the present study after providing written informed consent. The inclusion criteria defined obesity as a BMI of ≥37.5 kg/m2 or ≥32.5 kg/m2 in the presence of obesity-related co-morbidities [4], [12], [13].
The study subjects were required to
Results
A total of 53 patients fulfilled the entry criteria and underwent LSG. Of the 53 patients, 24 were men and 29 were women. Their mean age was 46.5 ± 8.7 years, mean BMI was 45.2 ± 9.3 kg/m2, mean waist circumference was 117.8 ± 18.0 cm, and mean HbA1c was 8.4% ± 1.6%. The mean duration of T2DM was 4.2 ± 5.0 years, and the mean duration of medication use was 4.0 ± 4.7 years (Table 1).
Before LSG, 48 patients (79%) were taking antidiabetic medication (oral hypoglycemic agents and/or insulin) and 5
Discussion
The gastric band operation and LSG have gained importance in recent years because of their ability to cause weight loss. LSG causes weight loss by a direct reduction of the stomach volume. This procedure is relatively safe, and the short-term outcomes have been promising [11]. LSG is relatively less time consuming and can be performed using a laparoscope.
In a recent study, Vidal et al. [15] reported on the benefits of LSG in 39 morbidly obese patients with T2DM. Their patients experienced a 63%
Conclusion
Our results have shown that LSG is an effective adjunct in the treatment of T2DM in obese individuals. The possible mechanisms for this need further investigation.
Disclosures
The authors have no commercial associations that might be a conflict of interest in relation to this article.
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