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A tissue-specific endothelial cell molecule involved in lymphocyte homing

Abstract

An endothelial cell surface molecule that is selectively expressed in mucosal organs is required for lymphocyte homing to mucosal lymphoid tissues. This 'vascular addressin' appears to function as a tissue-specific marker or address signal for recognition by lymphocytes circulating in the blood.

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Streeter, P., Berg, E., Rouse, B. et al. A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature 331, 41–46 (1988). https://doi.org/10.1038/331041a0

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