Clinical-alimentary tractDyspepsia and Irritable Bowel Syndrome After a Salmonella Gastroenteritis Outbreak: One-Year Follow-up Cohort Study
Section snippets
Study Design
On June 23, 2002, an outbreak of AGE occurred in a Spanish village of 9004 inhabitants (Torroella de Mongrí) located in the Baix Empordà county (Catalonia) with 106,828 inhabitants. The cause was S enteritidis colonization of traditional cream cakes, all made in the same baker’s shop to celebrate Saint John’s Eve. A total of 1243 persons were affected; about 40% were Torroella residents, 40% from other villages of the same county, and 20% visitors. Information with demographic (name, age, sex,
Results
Demographic and clinical data at study entry are shown in Table 1. Almost all (96.1%) of the patients with AGE had eaten the infected cake; the origin of the infection in the remainder could have been interpersonal or another product from the same bakery also containing Salmonella. In the control group, 6.8% of subjects reported having eaten some type of cake bought at the same bakery where the infected cake was made.
The prevalence of dyspepsia before AGE was similar in patients and controls
Discussion
Several previous studies related AGE to development of IBS. Between 6% and 17% of patients attributed their IBS to an attack of gastroenteritis.6 Prospective investigations also found an increase in the prevalence of IBS after AGE, but data vary depending on the severity of the infection (ambulatory or hospitalized patients) and infectious agent (with Campylobacter and Shigella carrying more risk than S enteritidis). Moreover, in prospective studies, no control group was included to ascertain
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Supported in part by Grupo Menarini Spain and supported by grant PI042739 from Fondo de Investigaciones Sanitarias, Ministerio de Sanidad y Consumo, Spain.