Original ArticlesEfficacy, safety, and clinical outcomes of endoscopic mucosal resection: A study of 101 cases☆
Section snippets
Patients and methods
Data from 92 consecutive patients referred for EMR between February 1997 and September 2000 were retrospectively reviewed. The institutional review board of our hospital approved the data analysis and the reporting. All cases in which EMR was attempted or performed were included. Patients who had incomplete EMR at other institutions and were subsequently referred were also included. All lesions had been identified at prior endoscopic examinations, either at our institution or by referring
Results
One hundred one lesions were removed from 92 patients (Table 1).Patients (n = 92) Variable Patients (%) Average age in y (range) 65 (25-88) Male gender 53 (58) Lesion location (n = 101) Esophagus 19 (19) Stomach 14 (14) Duodenum 27 (27) Colon 29 (29) Rectum 12 (12) Indication Adenocarcinoma 11 (11) HGD 13 (13) Lesion of unknown pathology 10 (10) Adenoma 67 (67) Size (cm) 2 (0.5-7) Morphology Flat 6 (6) Nodular 21 (21) Sessile 70 (70) Carpet-like 4 (4)
Discussion
EMR is an alternative to surgery for patients with superficial neoplastic lesions of the digestive tract not amenable to endoscopic resection with standard electrocautery snare techniques. EMR has an advantage over endoscopic ablation therapy in that it provides a specimen for histologic analysis. By using such adjunctive elements as submucosal saline solution injection, modified snares, and suction cap devices, CR of an array of challenging lesions from throughout the digestive tract can be
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Reprint requests: Gregory G. Ginsberg, MD, Division of Gastroenterology, Ravdin 3, Hospital of University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104.