1932

Abstract

MAP kinases are among the most ancient signal transduction pathways and are widely used throughout evolution in many physiological processes. In mammalian species, MAP kinases are involved in all aspects of immune responses, from the initiation phase of innate immunity, to activation of adaptive immunity, and to cell death when immune function is complete. In this review, we summarize recent progress in understanding the function and regulation of MAP kinase pathways in these phases of immune responses.

Keyword(s): ERKhelper T Cellsinnate immunityJNKp38
Loading

Article metrics loading...

/content/journals/10.1146/annurev.immunol.20.091301.131133
2002-04-01
2024-03-28
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.immunol.20.091301.131133
Loading
/content/journals/10.1146/annurev.immunol.20.091301.131133
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error