Inflammatory bowel disease and pregnancy

Inflamm Bowel Dis. 2001 May;7(2):146-57. doi: 10.1097/00054725-200105000-00011.

Abstract

Most women with inflammatory bowel disease who desire to become pregnant can expect to conceive successfully, carry to term, and deliver a healthy infant. However, the management of inflammatory bowel disease during pregnancy remains challenging, and some women with ulcerative colitis or Crohn's disease will have difficulty becoming pregnant or have increased disease symptoms while pregnant. Control of disease activity before conception and during pregnancy is critical to optimize both maternal and fetal health. The natural history of inflammatory bowel disease during pregnancy will be reviewed and the medical and surgical therapy discussed.

Publication types

  • Review

MeSH terms

  • Adult
  • Aminosalicylic Acids / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Colitis, Ulcerative / complications*
  • Colitis, Ulcerative / drug therapy
  • Colitis, Ulcerative / physiopathology
  • Crohn Disease / complications*
  • Crohn Disease / drug therapy
  • Crohn Disease / physiopathology
  • Female
  • Fertility
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Inflammatory Bowel Diseases / complications
  • Inflammatory Bowel Diseases / drug therapy
  • Inflammatory Bowel Diseases / physiopathology
  • Mesalamine / therapeutic use
  • Patient Education as Topic / methods
  • Pregnancy Complications* / drug therapy
  • Pregnancy Complications* / physiopathology
  • Pregnancy*
  • Sulfasalazine / therapeutic use
  • Surgical Procedures, Operative

Substances

  • Aminosalicylic Acids
  • Anti-Bacterial Agents
  • Immunosuppressive Agents
  • Sulfasalazine
  • Mesalamine