Helicobacter and gastric MALT lymphoma

M Stolte; E Bayerdörffer; A Morgner; B Alpen; T Wündisch; C Thiede; A Neubauer

doi:10.1136/gut.50.suppl_3.iii19

Helicobacter and gastric MALT lymphoma

Gut. 2002 May;50 Suppl 3(Suppl 3):III19-24. doi: 10.1136/gut.50.suppl_3.iii19.

Authors

M Stolte¹, E Bayerdörffer, A Morgner, B Alpen, T Wündisch, C Thiede, A Neubauer

Affiliation

¹ Institut für Pathologie, Klinikum Bayreuth, 95445 Bayreuth, Germany. pathologie.klinikum@bnbt.de

Abstract

Helicobacter pylori infection is a pre-MALT lymphoma condition. H pylori eradication leads to complete remission in 80% of low grade stage E1 lymphomas, with a yearly recurrence rate of approximately 5%. The possibility for complete remission in high grade lymphomas needs to be investigated in prospective studies. In addition, the significance of persistent B cell monoclonality (stable disease? danger of relapse? regression of monoclonality?) needs to be investigated in follow up studies.

Publication types

Review

MeSH terms

Animals
Biopsy
Disease Progression
Gastric Mucosa / microbiology
Gastric Mucosa / pathology
Gastritis / drug therapy
Gastritis / microbiology*
Helicobacter Infections / complications*
Helicobacter Infections / drug therapy
Helicobacter pylori*
Humans
Lymphoma, B-Cell, Marginal Zone / drug therapy
Lymphoma, B-Cell, Marginal Zone / microbiology*
Lymphoma, B-Cell, Marginal Zone / pathology
Remission Induction
Stomach Neoplasms / drug therapy
Stomach Neoplasms / microbiology*
Stomach Neoplasms / pathology