The role of Th1/Th2 polarization in mucosal immunity

Nat Med. 2002 Jun;8(6):567-73. doi: 10.1038/nm0602-567.

Abstract

Mucosal immunity relies on the delicate balance between antigen responsiveness and tolerance. The polarization of T helper cells plays a key role in maintaining or disrupting this equilibrium.

Publication types

  • Review

MeSH terms

  • Animals
  • Asthma / immunology
  • CD4-Positive T-Lymphocytes / immunology
  • Cell Polarity
  • Humans
  • Immunity, Mucosal / physiology*
  • Inflammatory Bowel Diseases / immunology
  • Models, Immunological
  • Th1 Cells / immunology
  • Th1 Cells / physiology*
  • Th2 Cells / immunology
  • Th2 Cells / physiology*