OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells

Gastroenterology. 2009 Jul;137(1):15-7. doi: 10.1053/j.gastro.2009.05.035. Epub 2009 May 18.

Authors

Laurens G van der Flier¹, Andrea Haegebarth, Daniel E Stange, Marc van de Wetering, Hans Clevers

Affiliation

¹ Hubrecht Institute, KNAW & University Medical Center Utrecht, Utrecht, The Netherlands.

PMID: 19450592
DOI: 10.1053/j.gastro.2009.05.035

No abstract available

MeSH terms

Adenocarcinoma / metabolism*
Adenocarcinoma / pathology
Biomarkers, Tumor / metabolism*
Colorectal Neoplasms / metabolism*
Colorectal Neoplasms / pathology
Granulocyte Colony-Stimulating Factor / metabolism*
Humans
Intestinal Mucosa / metabolism*
Intestines / pathology
Neoplastic Stem Cells / metabolism*
Neoplastic Stem Cells / pathology
Receptors, G-Protein-Coupled / metabolism
Stem Cells / metabolism*
Stem Cells / pathology

Substances

Biomarkers, Tumor
LGR5 protein, human
OLFM4 protein, human
Receptors, G-Protein-Coupled
Granulocyte Colony-Stimulating Factor