Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

Nat Biotechnol. 2013 Aug;31(8):681-3. doi: 10.1038/nbt.2661.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • CRISPR-Associated Proteins / genetics*
  • CRISPR-Cas Systems / genetics*
  • Gene Targeting / methods*
  • Inverted Repeat Sequences / genetics*
  • Mice
  • Mice, Knockout
  • Mutation
  • RNA / genetics
  • Rats
  • Zebrafish / genetics

Substances

  • CRISPR-Associated Proteins
  • RNA