Remission of Crohn's disease after human immunodeficiency virus infection

S P James

doi:10.1016/s0016-5085(88)80094-5

Remission of Crohn's disease after human immunodeficiency virus infection

Gastroenterology. 1988 Dec;95(6):1667-9. doi: 10.1016/s0016-5085(88)80094-5.

Author

S P James¹

Affiliation

¹ Mucosal Immunity Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.

PMID: 2903112
DOI: 10.1016/s0016-5085(88)80094-5

Abstract

A patient with an 18-yr history of Crohn's disease of the colon became infected with the human immunodeficiency virus. The patient had a complete remission of gastrointestinal symptoms in association with progressive immunodeficiency. This finding suggests that CD4 T cells and an intact immune response play a central role in the pathogenesis of Crohn's disease.

Publication types

Case Reports

MeSH terms

Acquired Immunodeficiency Syndrome / immunology*
Adult
CD4-Positive T-Lymphocytes / immunology*
Crohn Disease / immunology*
Humans
Male
Time Factors