Abstract
An endothelial cell surface molecule that is selectively expressed in mucosal organs is required for lymphocyte homing to mucosal lymphoid tissues. This 'vascular addressin' appears to function as a tissue-specific marker or address signal for recognition by lymphocytes circulating in the blood.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antibodies, Monoclonal / immunology
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Antigens, Surface
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Cadherins
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Cell Adhesion
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Cell Adhesion Molecules*
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Cell Movement*
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Endothelium, Vascular / analysis*
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Endothelium, Vascular / immunology
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Lymph Nodes / metabolism
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Lymphocytes / physiology*
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Membrane Glycoproteins / immunology
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Membrane Glycoproteins / physiology*
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Mice
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Mice, Inbred BALB C
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Organ Specificity
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Peyer's Patches / metabolism
Substances
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Antibodies, Monoclonal
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Antigens, Surface
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Cadherins
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Cdh2 protein, mouse
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Cell Adhesion Molecules
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Membrane Glycoproteins