Abstract
The resistance to exonuclease digestion of two regions of chromatin at the 5' end of heat-shock genes in Drosophila implies they have protein bound to them. The pattern of resistance before and after induction of gene expression suggests that heat-shock genes are activated by the sequential binding of at least two protein factors.
MeSH terms
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Animals
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Base Sequence
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Chromatin / physiology
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Chromatin / ultrastructure*
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DNA-Binding Proteins / physiology
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Deoxyribonucleases
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Drosophila melanogaster / genetics
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Exonucleases
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Gene Expression Regulation*
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Genes
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Heat-Shock Proteins / genetics*
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Operon
Substances
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Chromatin
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DNA-Binding Proteins
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Heat-Shock Proteins
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Deoxyribonucleases
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Exonucleases