Intermediate filaments as mechanical integrators of cellular space

Nature. 1980 Jan 17;283(5744):249-256. doi: 10.1038/283249a0.

Abstract

Five chemically distinct classes of intermediate filaments can be identified within higher eukaryotic cells. Each class is characteristic of a particular cell type. These filaments may function to integrate mechanically the various structures of the cytoplasmic space in a way that is tailored to the differentiated state of the cell.

MeSH terms

  • Actinin / metabolism
  • Animals
  • Cytoskeleton / physiology*
  • Eukaryotic Cells / ultrastructure
  • Keratins / metabolism
  • Muscle Proteins / metabolism*
  • Muscles / ultrastructure*
  • Nerve Tissue Proteins / metabolism
  • Neuroglia / ultrastructure*
  • Neurons / ultrastructure*
  • Phosphoproteins / metabolism
  • Proteins / metabolism
  • Species Specificity

Substances

  • Muscle Proteins
  • Nerve Tissue Proteins
  • Phosphoproteins
  • Proteins
  • Actinin
  • Keratins