Abstract
In 90 volunteers participating in a vaccine-development programme consumption of beer more than 3 days a week was linked with high stomach acid output, and smoking of cannabis greater than 2 days a week was linked with low acid output. In 92 volunteers challenged with Vibrio cholerae or enterotoxigenic Escherichia coli, heavy use of cannabis was associated with more voluminous diarrhoea. Cannabis use may be an important factor predisposing to severe diarrhoea.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Achlorhydria / complications*
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Achlorhydria / microbiology
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Adult
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Beer
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Cannabis*
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Cholera / etiology*
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Cholera / microbiology
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Diarrhea / etiology
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Diarrhea / microbiology
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Enterotoxins / adverse effects
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Escherichia coli / pathogenicity
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Escherichia coli Infections / etiology
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Escherichia coli Infections / microbiology
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Female
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Gastric Juice / metabolism*
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Humans
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Male
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Vibrio cholerae / pathogenicity