Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now?

Immunol Today. 1994 Feb;15(2):48-51. doi: 10.1016/0167-5699(94)90131-7.

Abstract

Vaccination with tumor cells that have been engineered to express cytokine genes has been developed in animal models as a novel form of tumor therapy. Mario Colombo and Guido Forni assess the current situation and suggest a way forward.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cytokines / genetics
  • Cytokines / immunology*
  • Gene Expression
  • Gene Transfer Techniques*
  • Immunotherapy*
  • Mice
  • Neoplasms, Experimental / genetics
  • Neoplasms, Experimental / immunology
  • Neoplasms, Experimental / therapy*
  • Transfection
  • Vaccination

Substances

  • Cytokines