The prevertebral ganglia which are a constitutive part of the sympathetic system have long been considered as a simple relay on this efferent pathway. In fact, these ganglia must be considered as true peripheral nervous centres. They possess various integrative properties, such as projections of central and peripheral inputs onto the ganglionic neurones, gating of these projections and pacemaker activity of the ganglionic neurones. These properties explain the ability of these ganglia to participate in the regulation of various visceral functions, including digestive tract motility.