Beneficial effect of lovastatin on sphincter of Oddi dyskinesia in hypercholesterolemia and hypertriglyceridemia

Am J Gastroenterol. 1997 May;92(5):900-2.

Abstract

This report describes an impaired sphincter of Oddi relaxation function in relation to hypercholesterolemia and hypertriglyceridemia. As indicated by repetitive amyl nitrite-augmented quantitative hepatobiliary scintgraphy, normalization of serum lipids by means of diet and a 3-month treatment period with 20 mg of lovastatin per day resulted in an improvement of sphincter of Oddi relaxation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anticholesteremic Agents / therapeutic use*
  • Bile Duct Diseases / drug therapy
  • Bile Duct Diseases / etiology
  • Female
  • Humans
  • Hypercholesterolemia / complications
  • Hypercholesterolemia / drug therapy*
  • Hypertriglyceridemia / complications
  • Hypertriglyceridemia / drug therapy*
  • Lovastatin / therapeutic use*
  • Movement Disorders / drug therapy
  • Movement Disorders / etiology
  • Sphincter of Oddi / drug effects*

Substances

  • Anticholesteremic Agents
  • Lovastatin