Glucocorticoid-induced osteoporosis: both in vivo and in vitro concentrations of glucocorticoids higher than physiological levels attenuate osteoblast differentiation

J Bone Miner Res. 1998 Dec;13(12):1822-6. doi: 10.1359/jbmr.1998.13.12.1822.

Authors

Y Ishida¹, J N Heersche

Affiliation

¹ Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.; Department of Orthopaedic Surgery, Yamaguchi University School of Medicine, Yamaguchi, Japan.

PMID: 9844099
DOI: 10.1359/jbmr.1998.13.12.1822

No abstract available

Publication types

Review

MeSH terms

Animals
Cell Differentiation / drug effects
Dose-Response Relationship, Drug
Glucocorticoids / administration & dosage
Glucocorticoids / adverse effects*
Humans
Osteoblasts / cytology*
Osteogenesis / drug effects*
Osteoporosis / chemically induced*

Substances

Glucocorticoids