Worldwide, the zebrafish has become a popular model for biomedical research and (eco)
toxicology. Particularly the use of embryos is receiving increasing attention, since they are …

Summary T helper type 17 (Th17) and regulatory T (Treg) cells are active players in the
establishment of tolerance and defence. These attributes of the immune system enmesh to …

How the semi-allogeneic fetus is tolerated by the maternal immune system remains a
fascinating phenomenon. Despite extensive research activity in this field, the mechanisms …

Manufacturing enterprises are currently facing substantial challenges with regard to
disruptive concepts such as the Internet of Things, Cyber Physical Systems or Cloud-based …

Background Remarkable financial and political efforts have been focused on the reduction
of child mortality during the past few decades. Timely measurements of levels and trends in …

Epigenetic misregulation is consistent with various non-Mendelian features of schizophrenia
and bipolar disorder. To date, however, few studies have investigated the role of DNA …

This paper addresses a novel method of topology and shape optimization. The basic idea is
the iterative positioning of new holes (so-called “bubbles”) into the present structure of the …

A two-part comparative study that assesses the results of planning experience in more than
100 mixed-economy and socialized countries in Africa, Asia, Europe, and the Americas. Part …

Erythroid cells undergo enucleation and the removal of organelles during terminal
differentiation,,. Although autophagy has been suggested to mediate the elimination of …

Piezo ion channels are activated by various types of mechanical stimuli and function as
biological pressure sensors in both vertebrates and invertebrates. To date, mechanical …