Intestinal barrier function regulates transport and host defense mechanisms at the mucosal
interface with the outside world. Transcellular and paracellular fluxes are tightly controlled …

Inflammatory bowel disease is characterized by a chronic inflammation of the intestinal
mucosa. The mucosal epithelium of the alimentary tract constitutes a key element of the …

Anemia is the most prevalent extraintestinal complication of IBD. It can affect quality of life
and ability to work, and can also increase the hospitalization rate in patients with IBD …

Anaemia is the most common systemic complication and extraintestinal manifestation of
inflammatory bowel disease [IBD]. 1–3 In the majority of cases, IBD-associated anaemia is a …

Background: After various forms of superficial injury, mucosal integrity is re-established by
rapid migration of epithelial cells across the wound margins in a process termed restitution …

OBJECTIVES Anemia is a frequent complication in patients with inflammatory bowel disease
(IBD). The optimal route for iron supplementation to replenish iron stores has not been …

The mucosal epithelium of the alimentary tract represents a crucial barrier to a broad
spectrum of noxious and immunogenic substances within the intestinal lumen. An …

Toll-like receptors (TLRs) are key components of the innate immune system that trigger
antimicrobial host defense responses. The aim of the present study was to analyze the …

This ECCO topical review of the European Crohn's and Colitis Organisation [ECCO] focused
on prediction, diagnosis, and management of fibrostenosing Crohn's disease [CD]. The …

Galectin-2 is structurally closely related to galectin-1, but has a distinct expression profile
primarily confined to the gastrointestinal tract. Prominent differences in the proximal …