Alpha 1-antitrypsin deficiency is an inherited metabolic disorder that predisposes the
affected individual to chronic pulmonary disease, in addition to chronic liver disease …

Abnormalities in protein and energy metabolism occur frequently in chronic liver disease
with resultant malnutrition. Since many of the complications of liver disease (such as …

To more fully characterize the available evidence supporting the recommendations, the
AASLD Practice Guidelines Committee has adopted the classification used by the Grading …

Connective tissue diseases such as systemic lupus erythematosus (SLE), rheumatoid
arthritis, Sjögren's syndrome, and scleroderma are systemic disorders that may have an …

Peroxidative decomposition of cellular membrane lipids is a postulated mechanism of
hepatocellular injury in parenchymal iron overload. In the present study, we looked for direct …

BACKGROUND Hereditary hemochromatosis (HH) is the most common, identified, genetic
disorder in the Caucasian population. Although its geographic distribution is worldwide, it is …

The possibility of using liposomes as carriers of drugs has been investigated in three
patients with metastatic cancer. The fate of liposomes injected into the circulation was …

This article addresses the role of the liver in normal glucose homeostasis and discusses a
variety of liver conditions associated with abnormal glucose homeostasis. This association …

Hepatic iron concentration has consistently been observed as being directly correlated with
the response to interferon therapy in chronic hepatitis C virus (HCV). We therefore …

A patient with protein‐losing gastroenteropathy and egg allergy has been shown to have a
previously unrecognized organic aciduria, d‐2‐hydroxyglutaric aciduria. The observations …