Highlights•Most research on the microbiota–gut brain axis has been conducted on
animals.•We reviewed recent human studies on gut microbiota and mental health.•Small …

To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …

Impaired appetite and weight changes are commonly seen in patients with depression, but
the pathophysiology behind this imbalance between energy intake and energy expenditure …

Background: Because the projected increase in the number of diabetic patients is expected
to strain the capabilities of health care providers worldwide, we are challenged to find ways …

Background & Aims It is unclear whether the identification of individuals at risk of cirrhosis
using non-invasive tests can be improved by repeated measurements. Herein, we tested …

Objective IBS is a common gut disorder of uncertain pathogenesis. Among other factors,
genetics and certain foods are proposed to contribute. Congenital sucrase–isomaltase …

Objective IBS shows genetic predisposition, but adequately powered gene-hunting efforts
have been scarce so far. We sought to identify true IBS genetic risk factors by means of …

Background Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder,
affecting more than 10% of the general population worldwide. Although a genetic …

Background & Aims Noninvasive scoring systems are used to identify persons with
advanced liver fibrosis. We investigated the ability of scoring systems to identify individuals …

Objective The ethiopathogenesis of irritable bowel syndrome (IBS) is unknown. While a link
to the gut microbiome is postulated, the heterogeneity of the healthy gut makes it difficult to …