[PDF][PDF] Innate immune training of granulopoiesis promotes anti-tumor activity
Trained innate immunity, induced via modulation of mature myeloid cells or their bone
marrow progenitors, mediates sustained increased responsiveness to secondary …
marrow progenitors, mediates sustained increased responsiveness to secondary …
Complex regional pain syndrome: diagnosis and treatment
M Freedman, AC Greis, L Marino… - Physical Medicine …, 2014 - pmr.theclinics.com
Complex regional pain syndrome (CRPS) is characterized by pain that is out of proportion to
the usual time or degree of a specific lesion. It does not present within the distribution of one …
the usual time or degree of a specific lesion. It does not present within the distribution of one …
[HTML][HTML] DNA methylation and transcription patterns in intestinal epithelial cells from pediatric patients with inflammatory bowel diseases differentiate disease subtypes …
Background & Aims We analyzed DNA methylation patterns and transcriptomes of primary
intestinal epithelial cells (IEC) of children newly diagnosed with inflammatory bowel …
intestinal epithelial cells (IEC) of children newly diagnosed with inflammatory bowel …
[PDF][PDF] Epigenomic profiling of human CD4+ T cells supports a linear differentiation model and highlights molecular regulators of memory development
The impact of epigenetics on the differentiation of memory T (Tmem) cells is poorly defined.
We generated deep epigenomes comprising genome-wide profiles of DNA methylation …
We generated deep epigenomes comprising genome-wide profiles of DNA methylation …
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
Objective Vedolizumab, a monoclonal antibody directed against the integrin heterodimer
α4β7, is approved for the treatment of Crohn's disease and ulcerative colitis. The efficacy of …
α4β7, is approved for the treatment of Crohn's disease and ulcerative colitis. The efficacy of …
Enhancement of heat transfer in a fin-tube heat exchanger using rectangular winglet type vortex generators
The present study simulates the air flow through fin-tube type heat exchangers with
rectangular winglet pairs (RWP) of half the channel height as vortex generators (VG). The …
rectangular winglet pairs (RWP) of half the channel height as vortex generators (VG). The …
Augmentation of heat transfer by creation of streamwise longitudinal vortices using vortex generators
This paper summarizes the current state of the art related to improvement of the heat
exchanger surfaces using streamwise longitudinal vortices. Primarily, the improvements …
exchanger surfaces using streamwise longitudinal vortices. Primarily, the improvements …
Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction
F Schmidt, N Gasparoni, G Gasparoni… - Nucleic acids …, 2017 - academic.oup.com
The binding and contribution of transcription factors (TF) to cell specific gene expression is
often deduced from open-chromatin measurements to avoid costly TF ChIP-seq assays …
often deduced from open-chromatin measurements to avoid costly TF ChIP-seq assays …
Effects of different orientations of winglet arrays on the performance of plate-fin heat exchangers
Numerical investigations pertaining to heat transfer enhancement of a plate-fin heat
exchanger using two rows of winglet type vortex generators (VG) have been performed in …
exchanger using two rows of winglet type vortex generators (VG) have been performed in …
Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease
Objective An inadequate host response to the intestinal microbiota likely contributes to the
manifestation and progression of human inflammatory bowel disease (IBD). However …
manifestation and progression of human inflammatory bowel disease (IBD). However …