User profiles for "author:Feargal J Ryan"

Feargal J. Ryan

NHMRC Investigator, SAHMRI
Verified email at sahmri.com
Cited by 4268

Tumour-associated and non-tumour-associated microbiota in colorectal cancer

B Flemer, DB Lynch, JMR Brown, IB Jeffery, FJ Ryan… - Gut, 2017 - gut.bmj.com
Objective A signature that unifies the colorectal cancer (CRC) microbiota across multiple
studies has not been identified. In addition to methodological variance, heterogeneity may …

[HTML][HTML] Regulation of prefrontal cortex myelination by the microbiota

AE Hoban, RM Stilling, FJ Ryan, F Shanahan… - Translational …, 2016 - nature.com
The prefrontal cortex (PFC) is a key region implicated in a range of neuropsychiatric
disorders such as depression, schizophrenia and autism. In parallel, the role of the gut …

[HTML][HTML] Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection

FJ Ryan, CM Hope, MG Masavuli, MA Lynn… - BMC medicine, 2022 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …

[PDF][PDF] The human gut virome is highly diverse, stable, and individual specific

AN Shkoporov, AG Clooney, TDS Sutton, FJ Ryan… - Cell host & …, 2019 - cell.com
The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain
uncharacterized, and their roles in shaping the gut microbiome and in impacting on human …

[PDF][PDF] Whole-virome analysis sheds light on viral dark matter in inflammatory bowel disease

AG Clooney, TDS Sutton, AN Shkoporov, RK Holohan… - Cell host & …, 2019 - cell.com
The human gut virome is thought to significantly impact the microbiome and human health.
However, most virome analyses have been performed on a limited fraction of known viruses …

Microbes & neurodevelopment–Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala

RM Stilling, FJ Ryan, AE Hoban, F Shanahan… - Brain, behavior, and …, 2015 - Elsevier
The mammalian amygdala is a key emotional brain region for eliciting social behaviour,
critically involved in anxiety and fear-related behaviours, and hence a focus of research on …

[HTML][HTML] Ranking microbiome variance in inflammatory bowel disease: a large longitudinal intercontinental study

AG Clooney, J Eckenberger, E Laserna-Mendieta… - Gut, 2021 - gut.bmj.com
Objective The microbiome contributes to the pathogenesis of inflammatory bowel disease
(IBD) but the relative contribution of different lifestyle and environmental factors to the …

[PDF][PDF] Biology and taxonomy of crAss-like bacteriophages, the most abundant virus in the human gut

E Guerin, A Shkoporov, SR Stockdale, AG Clooney… - Cell host & …, 2018 - cell.com
CrAssphages represent the most abundant virus in the human gut microbiota, but the lack of
available genome sequences for comparison has kept them enigmatic. Recently, sequence …

[HTML][HTML] Reproducible protocols for metagenomic analysis of human faecal phageomes

AN Shkoporov, FJ Ryan, LA Draper, A Forde… - Microbiome, 2018 - Springer
Background Recent studies have demonstrated that the human gut is populated by complex,
highly individual and stable communities of viruses, the majority of which are …

[HTML][HTML] SPINGO: a rapid species-classifier for microbial amplicon sequences

G Allard, FJ Ryan, IB Jeffery, MJ Claesson - BMC bioinformatics, 2015 - Springer
Background Taxonomic classification is a corner stone for the characterisation and
comparison of microbial communities. Currently, most existing methods are either slow …