PASSCLAIM1—Gut health and immunity

JH Cummings, JM Antoine, F Azpiroz… - European Journal of …, 2004 - Springer
Background: The gut and immune system form a complex integrated structure that has
evolved to provide effective digestion and defence against ingested toxins and pathogenic …

Ambulatory reflux monitoring for diagnosis of gastro‐esophageal reflux disease: update of the Porto consensus and recommendations from an international …

S Roman, CP Gyawali, E Savarino… - …, 2017 - Wiley Online Library
Background An international group of experts evaluated and revised recommendations for
ambulatory reflux monitoring for the diagnosis of gastro‐esophageal reflux disease (GERD) …

Functional dyspepsia

P Enck, F Azpiroz, G Boeckxstaens… - Nature Reviews …, 2017 - nature.com
Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders.
Functional dyspepsia comprises three subtypes with presumed different pathophysiology …

The origin of symptoms on the brain-gut axis in functional dyspepsia

F Mearin, M Cucala, F Azpiroz, JR Malagelada - Gastroenterology, 1991 - Elsevier
It was hypothesized that symptoms in functional dyspepsia are originated by an altered
mechanism at the brain-gut axis (one or several) in the process of gastric accommodation to …

Gastric tone measured by an electronic barostat in health arid postsurgical gastroparesis

F Azpiroz, JR Malagelada - Gastroenterology, 1987 - Elsevier
Using a gastric barostat we have studied interdigestive variations in gastric tone and its
response to gastric distention in 17 healthy volunteers and 5 patients with postsurgical …

[HTML][HTML] Reduction of butyrate-and methane-producing microorganisms in patients with Irritable Bowel Syndrome

M Pozuelo, S Panda, A Santiago, S Mendez… - Scientific reports, 2015 - nature.com
The pathophysiology of irritable bowel syndrome (IBS) remains unclear. Here we
investigated the microbiome of a large cohort of patients to identify specific signatures for …

Diarrhoea-predominant irritable bowel syndrome: an organic disorder with structural abnormalities in the jejunal epithelial barrier

C Martínez, B Lobo, M Pigrau, L Ramos… - Gut, 2013 - gut.bmj.com
Objective Recently, the authors demonstrated altered gene expression in the jejunal
mucosa of diarrhoea-predominant irritable bowel syndrome patients (IBS-D); specifically, the …

Anorectal functional testing: review of collective experience

F Azpiroz, P Enck, WE Whitehead - Official journal of the …, 2002 - journals.lww.com
Anorectal manometry includes a number of specific tests that are helpful in the diagnostic
assessment of patients with fecal incontinence and constipation; their purpose is to …

[HTML][HTML] Storage conditions of intestinal microbiota matter in metagenomic analysis

S Cardona, A Eck, M Cassellas, M Gallart, C Alastrue… - BMC microbiology, 2012 - Springer
Background The structure and function of human gut microbiota is currently inferred from
metagenomic and metatranscriptomic analyses. Recovery of intact DNA and RNA is …

Selective dysfunction of mechanosensitive intestinal afferents in irritable bowel syndrome

AM Accarino, F Azpiroz, JR Malagelada - Gastroenterology, 1995 - Elsevier
Background/Aims: Experimental studies have shown gut hypersensitivity in irritable bowel
syndrome. The aim of this study was to determine whether heightened perception of gut …