User profiles for "author:I D Iliev"

Iliyan D. Iliev

WCM, Cornell University; Mycobiota and Mucosal Immunology Laboratory; Director …
Verified email at med.cornell.edu
Cited by 9069

The mycobiota: interactions between commensal fungi and the host immune system

DM Underhill, ID Iliev - Nature Reviews Immunology, 2014 - nature.com
The body is host to a wide variety of microbial communities from which the immune system
protects us and that are important for the normal development of the immune system and for …

Regulation of inflammation by microbiota interactions with the host

JM Blander, RS Longman, ID Iliev, GF Sonnenberg… - Nature …, 2017 - nature.com
The study of the intestinal microbiota has begun to shift from cataloging individual members
of the commensal community to understanding their contributions to the physiology of the …

Fungal dysbiosis: immunity and interactions at mucosal barriers

ID Iliev, I Leonardi - Nature Reviews Immunology, 2017 - nature.com
Fungi and mammals share a co-evolutionary history and are involved in a complex web of
interactions. Studies focused on commensal bacteria suggest that pathological changes in …

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

ID Iliev, VA Funari, KD Taylor, Q Nguyen, CN Reyes… - Science, 2012 - science.org
The intestinal microflora, typically equated with bacteria, influences diseases such as
obesity and inflammatory bowel disease. Here, we show that the mammalian gut contains a …

[PDF][PDF] Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

I Leonardi, IH Gao, WY Lin, M Allen, XV Li, WD Fiers… - Cell, 2022 - cell.com
Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …

[PDF][PDF] A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors

AB Dohlman, J Klug, M Mesko, IH Gao, SM Lipkin… - Cell, 2022 - cell.com
Fungal microorganisms (mycobiota) comprise a small but immunoreactive component of the
human microbiome, yet little is known about their role in human cancers. Pan-cancer …

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells

ID Iliev, I Spadoni, E Mileti, G Matteoli, A Sonzogni… - Gut, 2009 - gut.bmj.com
Objective: In mice, a subpopulation of gut dendritic cells (DCs) expressing CD103 drives the
development of regulatory T (Treg) cells. Further, it was recently described that the cross-talk …

Laboratory mice born to wild mice have natural microbiota and model human immune responses

SP Rosshart, J Herz, BG Vassallo, A Hunter, MK Wall… - Science, 2019 - science.org
INTRODUCTION Laboratory mice are a mainstay of biomedical research and have been
instrumental for many important discoveries in the field of immunology. However, there are …

Immune regulation by fungal strain diversity in inflammatory bowel disease

XV Li, I Leonardi, GG Putzel, A Semon, WD Fiers… - Nature, 2022 - nature.com
The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial
community colonizing the mammalian gastrointestinal tract and has an important role in …

[PDF][PDF] Immunological consequences of intestinal fungal dysbiosis

ML Wheeler, JJ Limon, AS Bar, CA Leal, M Gargus… - Cell host & …, 2016 - cell.com
Compared to bacteria, the role of fungi within the intestinal microbiota is poorly understood.
In this study we investigated whether the presence of a" healthy" fungal community in the gut …