Despite the success of antiretroviral therapy (ART) for people living with HIV, lifelong
treatment is required and there is no cure. HIV can integrate in the host genome and persist …

In response to the traditional emphasis on the rights, interests, and well-being of individual
research subjects, there has been growing attention focused on the importance of involving …

Summary The International Society for Stem Cell Research has updated its Guidelines for
Stem Cell Research and Clinical Translation in order to address advances in stem cell …

Background Safe and effective long-acting injectable agents for preexposure prophylaxis
(PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options …

Vulnerability is one of the least examined concepts in research ethics. Vulnerability was
linked in the Belmont Report to questions of justice in the selection of subjects. Regulations …

There is considerable confusion regarding the ethical appropriateness of using incentives in
research with human subjects. Previous work on determining whether incentives are …

Academic global health programs are growing rapidly in scale and number. Students of
many disciplines increasingly desire global health content in their curricula. Global health …

Importance Extenuating circumstances can trigger unplanned changes to randomized trials
and introduce methodological, ethical, feasibility, and analytical challenges that can …

PURPOSE Although involving patients in their own health care is known to be associated
with improved outcomes, this study was conducted to determine whether respecting persons …

Background: Given the high mortality rate for patients with end-stage kidney disease
receiving dialysis and the efficacy and safety of hepatitis C virus (HCV) treatments …