Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo
MS Mroz, N Keating, JB Ward, R Sarker, S Amu… - Gut, 2014 - gut.bmj.com
Objective Bile acids are important regulators of intestinal physiology, and the nuclear bile
acid receptor, farnesoid X receptor (FXR), is emerging as a promising therapeutic target for …
acid receptor, farnesoid X receptor (FXR), is emerging as a promising therapeutic target for …
Ursodeoxycholic acid inhibits TNFα-induced IL-8 release from monocytes
AM O'Dwyer, NK Lajczak, JA Keyes… - American Journal …, 2016 - journals.physiology.org
Monocytes are critical to the pathogenesis of inflammatory bowel disease (IBD) as they
infiltrate the mucosa and release cytokines that drive the inflammatory response …
infiltrate the mucosa and release cytokines that drive the inflammatory response …
Chronic regulation of colonic epithelial secretory function by activation of G protein‐coupled receptors
F Toumi, M Frankson, JB Ward, OB Kelly… - …, 2011 - Wiley Online Library
Background Enteric neurotransmitters that act at G protein‐coupled receptors (GPCRs) are
well known to acutely promote epithelial Cl− and fluid secretion. Here we examined if acute …
well known to acutely promote epithelial Cl− and fluid secretion. Here we examined if acute …
Bacterial metabolism of Ursodeoxycholic Acid is necessary for its protective actions in a mouse model of intestinal inflammation
NK Lajczak, JB Ward, BJ Goggins, S Keely… - The FASEB …, 2017 - Wiley Online Library
Background Although inflammatory bowel disease (IBD) represents a significant health and
economic burden, current therapies are often ineffective. Altered intestinal epithelial barrier …
economic burden, current therapies are often ineffective. Altered intestinal epithelial barrier …
[CITATION][C] Modifier of Na+/K+-ATPase; Upregulated by Hydroxylase Inhibition in Colonic Epithelial Cells: Implications for Epithelial Secretory Function
JB Ward, CT Taylor, SJ Keely - Gastroenterology, 2011 - infona.pl
Modifier of Na+/K+-ATPase; Upregulated by Hydroxylase Inhibition in Colonic Epithelial Cells:
Implications for Epithelial Secretory Function × Close The Infona portal uses cookies, ie strings …
Implications for Epithelial Secretory Function × Close The Infona portal uses cookies, ie strings …
[CITATION][C] T1839 Farnesoid X-Receptor Agonists Inhibit Colonic Secretion In Vitro and In Vivo.
N Keating, MS Mroz, F Dunleavy, JB Ward, SJ Keely - Gastroenterology, 2010 - infona.pl
T1839 Farnesoid X-Receptor Agonists Inhibit Colonic Secretion In Vitro and In Vivo. × Close
The Infona portal uses cookies, ie strings of text saved by a browser on the user's device. The …
The Infona portal uses cookies, ie strings of text saved by a browser on the user's device. The …
[CITATION][C] 259 Hydroxylase Inhibition Attenuates Colonic Epithelial Secretory Function and Ameliorates Experimental Diarrhea
JB Ward, S Amu, CT Taylor, PG Fallon, SJ Keely - Gastroenterology, 2010 - infona.pl
259 Hydroxylase Inhibition Attenuates Colonic Epithelial Secretory Function and Ameliorates
Experimental Diarrhea × Close The Infona portal uses cookies, ie strings of text saved by a …
Experimental Diarrhea × Close The Infona portal uses cookies, ie strings of text saved by a …
[CITATION][C] Economic Feasibility: Multi-Purpose Stadium
JB Ward - King County (Seattle, 1971), 1971
[CITATION][C] Arms and the Man by George Bernard Shaw: Finding Joy in the Classic
JB Ward - 2006 - University of California, San Diego