Precancerous lesions in the stomach: from biology to clinical patient management

M Rugge, LG Capelle, R Cappellesso, D Nitti… - Best Practice & …, 2013 - Elsevier
Gastric cancer is the final step in a multi-stage cascade triggered by long-standing
inflammatory conditions (particularly Helicobacter pylori infection) resulting in atrophic …

Risk and epidemiological time trends of gastric cancer in Lynch syndrome carriers in the Netherlands

LG Capelle, NCT Van Grieken, HF Lingsma… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Although gastric cancer forms part of the Lynch syndrome tumor
spectrum, the risk of developing gastric cancer in Lynch syndrome families is unknown …

Identification of genetic loci associated with Helicobacter pylori serologic status

J Mayerle, CM den Hoed, C Schurmann, L Stolk… - Jama, 2013 - jamanetwork.com
Importance Helicobacter pylori is a major cause of gastritis and gastroduodenal ulcer
disease and can cause cancer. H pylori prevalence is as high as 90% in some developing …

Gastric MALT lymphoma: epidemiology and high adenocarcinoma risk in a nation-wide study

LG Capelle, AC de Vries, CWN Looman… - European Journal of …, 2008 - Elsevier
BACKGROUND: Gastric marginal zone non-Hodgkin lymphomas MALT type (gMALT) and
gastric adenocarcinomas (GC) are long-term complications of chronic Helicobacter pylori …

[HTML][HTML] Narrow band imaging for the detection of gastric intestinal metaplasia and dysplasia during surveillance endoscopy

LG Capelle, J Haringsma, AC de Vries… - Digestive diseases and …, 2010 - Springer
Background Surveillance of premalignant gastric lesions relies mainly on random biopsy
sampling. Narrow band imaging (NBI) may enhance the accuracy of endoscopic …

Surveillance of premalignant gastric lesions: a multicentre prospective cohort study from low incidence regions

WJ den Hollander, IL Holster, CM den Hoed… - Gut, 2019 - gut.bmj.com
Objective International guidelines recommend endoscopic surveillance of premalignant
gastric lesions. However, the diagnostic yield and preventive effect require further study. We …

Follow-up of premalignant lesions in patients at risk for progression to gastric cancer

CM den Hoed, IL Holster, LG Capelle, AC de Vries… - …, 2013 - thieme-connect.com
Background and study aims: A recent international guideline recommends surveillance of
premalignant gastric lesions for patients at risk of progression to gastric cancer. The aim of …

Individual risk stratification of gastric cancer: evolving concepts and their impact on clinical practice

M Rugge, LG Capelle, M Fassan - Best Practice & Research Clinical …, 2014 - Elsevier
Gastric cancer (GC) is the third leading cause of cancer-related death worldwide and it
mostly develops in long-standing inflammatory conditions, and Helicobacter pylori-gastritis …

[HTML][HTML] Comparison of the management of Helicobacter pylori infection between the older and younger European populations

P Jonaitis, OP Nyssen, IM Saracino, G Fiorini… - Scientific Reports, 2023 - nature.com
The prevalence of Helicobacter pylori remains high in the older population. Specific age-
related peculiarities may impact the outcomes of H. pylori treatment. The aim of the study …

Increased risk of esophageal squamous cell carcinoma in patients with gastric atrophy: independent of the severity of atrophic changes

AC de Vries, LG Capelle, CWN Looman… - … journal of cancer, 2009 - Wiley Online Library
An association between gastric atrophy and esophageal squamous cell carcinomas (ESCC)
has been described. However, the mechanism of this association is unknown. In this study …