User profiles for "author:Matthew Leighton"
Matthew LeightonGraduate Student, Simon Fraser University Verified email at sfu.ca Cited by 53 |
A mechanistic multicentre, parallel group, randomised placebo-controlled trial of mesalazine for the treatment of IBS with diarrhoea (IBS-D)
C Lam, W Tan, M Leighton, M Hastings, M Lingaya… - Gut, 2016 - gut.bmj.com
Introduction Immune activation has been reported in the mucosa of IBS patients with
diarrhoea (IBS-D), and some small studies have suggested that mesalazine may reduce …
diarrhoea (IBS-D), and some small studies have suggested that mesalazine may reduce …
Large multi‐centre pilot randomized controlled trial testing a low‐cost, tailored, self‐help smoking cessation text message intervention for pregnant smokers (MiQuit)
F Naughton, S Cooper, K Foster, J Emery… - …, 2017 - Wiley Online Library
Aims To estimate the effectiveness of pregnancy smoking cessation support delivered by
short message service (SMS) text message and key parameters needed to plan a definitive …
short message service (SMS) text message and key parameters needed to plan a definitive …
Environmental performance of green building code and certification systems
S Suh, S Tomar, M Leighton… - Environmental science & …, 2014 - ACS Publications
We examined the potential life-cycle environmental impact reduction of three green building
code and certification (GBCC) systems: LEED, ASHRAE 189.1, and IgCC. A recently …
code and certification (GBCC) systems: LEED, ASHRAE 189.1, and IgCC. A recently …
Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a …
MP Leighton, S Nundlall, T Starborg… - Human molecular …, 2007 - academic.oup.com
Disruption to endochondral ossification leads to delayed and irregular bone formation and
can result in a heterogeneous group of genetic disorders known as the chondrodysplasias …
can result in a heterogeneous group of genetic disorders known as the chondrodysplasias …
Multiple epiphyseal dysplasia mutations in MATN3 cause misfolding of the A‐domain and prevent secretion of mutant matrilin‐3
SL Cotterill, GC Jackson, MP Leighton… - Human …, 2005 - Wiley Online Library
Multiple epiphyseal dysplasia (MED) is a relatively common skeletal dysplasia that can
present in childhood with a variable phenotype of short stature and pain and stiffness in the …
present in childhood with a variable phenotype of short stature and pain and stiffness in the …
Inferring subsystem efficiencies in bipartite molecular machines
MP Leighton, DA Sivak - Physical Review Letters, 2023 - APS
Molecular machines composed of coupled subsystems transduce free energy between
different external reservoirs, in the process internally transducing energy and information …
different external reservoirs, in the process internally transducing energy and information …
Interoperability between ecoinvent ver. 3 and US LCI database: a case study
S Suh, M Leighton, S Tomar, C Chen - The International Journal of Life …, 2016 - Springer
Abstract Purpose Building a global Life Cycle Inventory (LCI) database from scratch with a
harmonized method and wide process coverage would require significant resources …
harmonized method and wide process coverage would require significant resources …
Dynamic and thermodynamic bounds for collective motor-driven transport
MP Leighton, DA Sivak - Physical Review Letters, 2022 - APS
Molecular motors work collectively to transport cargo within cells, with anywhere from one to
several hundred motors towing a single cargo. For a broad class of collective-transport …
several hundred motors towing a single cargo. For a broad class of collective-transport …
Performance scaling and trade-offs for collective motor-driven transport
MP Leighton, DA Sivak - New Journal of Physics, 2022 - iopscience.iop.org
Motor-driven intracellular transport of organelles, vesicles, and other molecular cargo is a
highly collective process. An individual cargo is often pulled by a team of transport motors …
highly collective process. An individual cargo is often pulled by a team of transport motors …
A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia
F Suleman, B Gualeni, HJ Gregson… - Human …, 2012 - Wiley Online Library
Pseudoachondroplasia (PSACH) results from mutations in cartilage oligomeric matrix
protein (COMP) and the p. D469del mutation within the type III repeats of COMP accounts for …
protein (COMP) and the p. D469del mutation within the type III repeats of COMP accounts for …