Objectives: This study provides an overview of the largest and longest-running colonoscopic
surveillance program for colorectal cancer (CRC) in patients with long-standing ulcerative …

Background Accurate optical characterisation and removal of small adenomas (< 10 mm) at
colonoscopy would allow hyperplastic polyps to be left in situ and surveillance intervals to …

Background Magnetic resonance enterography (MRE) and ultrasound are used to image
Crohn's disease, but their comparative accuracy for assessing disease extent and activity is …

Objective Ulcerative colitis (UC) is a dynamic disease with its severity continuously changing
over time. We hypothesised that the risk of colorectal neoplasia (CRN) in UC closely follows …

OBJECTIVES: The aim of this study was to identify risk factors associated with development
of high-grade dysplasia (HGD) or colorectal cancer (CRC) in ulcerative colitis (UC) patients …

Objective IBD confers an increased lifetime risk of developing colorectal cancer (CRC), and
colitis-associated CRC (CA-CRC) is molecularly distinct from sporadic CRC (S-CRC). Here …

Evidence links chronic inflammation with cancer, but cellular mechanisms involved in this
process remain unclear. We have demonstrated that in humans, inflammatory conditions …

Dendritic cells (DCs) either boost the immune system (enhancing immunity) or dampen it
(leading to tolerance). This dual effect explains their vital role in cancer development and …

Summary Background Screening for Barrett's oesophagus relies on endoscopy, which is
invasive and few who undergo the procedure are found to have the condition. We aimed to …

Sessile serrated adenomas/polyps (SSA/Ps) are frequently found in the proximal colon,
where the wall is thinner and easily damaged by diathermy during polypectomy, which also …