The aetiology and impact of malnutrition in paediatric inflammatory bowel disease

K Gerasimidis, P McGrogan… - Journal of Human …, 2011 - Wiley Online Library
Disease‐associated undernutrition of all types is very common in paediatric inflammatory
bowel disease (IBD). Recent weight loss remains one of the triad of clinical manifestations …

Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease

…, ER Nimmo, L Smith, PM Gillett, P McGrogan… - Gastroenterology, 2008 - Elsevier
Background & Aims: Childhood-onset inflammatory bowel disease (IBD) might be
etiologically different from adult-onset IBD. We analyzed disease phenotypes and …

The role of pro-inflammatory cytokines in inflammatory bowel disease growth retardation

SC Wong, VE Macrae, P McGrogan… - Journal of pediatric …, 2006 - journals.lww.com
Childhood inflammatory bowel disease (IBD) especially those with Crohn disease is
commonly complicated by faltering growth and pubertal delay. Pro-inflammatory cytokines …

Microbiota ofDe-NovoPediatric IBD: IncreasedFaecalibacterium Prausnitziiand Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis

…, J Bishop, DM Flynn, P McGrogan… - Official journal of the …, 2012 - journals.lww.com
OBJECTIVES: The gastrointestinal microbiota is considered important in inflammatory bowel
disease (IBD) pathogenesis. Discoveries fromestablisheddisease cohorts report reduced …

chronic granulomatous disease in the United Kingdom and Ireland: a comprehensive national patient-based registry

L Jones, P McGrogan, TJ Flood… - Clinical & …, 2008 - academic.oup.com
There are no epidemiological studies from the British Isles of chronic granulomatous
disease, characterized by recurrent, life-threatening bacterial and fungal infections and …

Extensive modulation of the fecal metagenome in children with Crohn's disease during exclusive enteral nutrition

…, M Bertz, M Blaut, R Hansen, P McGrogan… - Official journal of the …, 2015 - journals.lww.com
OBJECTIVES: Exploring associations between the gut microbiota and colonic inflammation
and assessing sequential changes during exclusive enteral nutrition (EEN) may offer clues …

The use of exclusive enteral nutrition for induction of remission in children with Crohn's disease demonstrates that disease phenotype does not influence clinical …

…, T Cardigan, V Garrick, P McGrogan… - Alimentary …, 2009 - Wiley Online Library
Background Exclusive enteral nutrition (EEN) achieves variable remission rates in patients
with Crohn's disease (CD). Aim To describe our experience of treating CD with an 8‐week …

Decline in presumptively protective gut bacterial species and metabolites are paradoxically associated with disease improvement in pediatric Crohn's disease during …

…, RK Russell, M Blaut, P McGrogan… - Inflammatory bowel …, 2014 - academic.oup.com
Background The gut microbiota is implicated in the pathogenesis of Crohn's disease (CD).
Exclusive enteral nutrition (EEN) is a successful treatment, but its mode of action remains …

A British Society of Paediatric Gastroenterology, Hepatology and Nutrition survey of the effectiveness and safety of adalimumab in children with inflammatory bowel …

…, S Vaish, P Rogers, P McGrogan… - Alimentary …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 33: 946–953 Summary Background Adalimumab is
efficacious therapy for adults with Crohn's disease (CD). Aim To summarise the United …

Clinical progress in the two years following a course of exclusive enteral nutrition in 109 paediatric patients with C rohn's disease

…, E Buchanan, AR Barclay, P McGrogan… - Alimentary …, 2013 - Wiley Online Library
Background Exclusive enteral nutrition (EEN) is an effective first line treatment for active
paediatric Crohn's disease (CD). Aim To examine the effect of EEN on short‐and long‐term …