User profiles for "author:Patricia G Wolf"

Patricia G. Wolf

Purdue University
Verified email at purdue.edu
Cited by 1779

Taurocholic acid metabolism by gut microbes and colon cancer

JM Ridlon, PG Wolf, HR Gaskins - Gut microbes, 2016 - Taylor & Francis
Colorectal cancer (CRC) is one of the most frequent causes of cancer death worldwide and
is associated with adoption of a diet high in animal protein and saturated fat. Saturated fat …

Relationship between microbiota of the colonic mucosa vs feces and symptoms, colonic transit, and methane production in female patients with chronic constipation

G Parthasarathy, J Chen, X Chen, N Chia… - Gastroenterology, 2016 - Elsevier
Background & Aims In fecal samples from patients with chronic constipation, the microbiota
differs from that of healthy subjects. However, the profiles of fecal microbiota only partially …

Race-dependent association of sulfidogenic bacteria with colorectal cancer

C Yazici, PG Wolf, H Kim, TWL Cross, K Vermillion… - Gut, 2017 - gut.bmj.com
Objective Colorectal cancer (CRC) incidence is higher in African Americans (AAs) compared
with non-Hispanic whites (NHWs). A diet high in animal protein and fat is an environmental …

Zinc enhances intestinal epithelial barrier function through the PI3K/AKT/mTOR signaling pathway in Caco-2 cells

Y Shao, PG Wolf, S Guo, Y Guo, HR Gaskins… - The Journal of …, 2017 - Elsevier
Zinc plays an important role in maintaining intestinal barrier function as well as modulating
cellular signaling recognition and protein kinase activities. The phosphatidylinositol 3-kinase …

H2 metabolism is widespread and diverse among human colonic microbes

PG Wolf, A Biswas, SE Morales, C Greening… - Gut …, 2016 - Taylor & Francis
Microbial molecular hydrogen (H2) cycling is central to metabolic homeostasis and microbial
composition in the human gastrointestinal tract. Molecular H2 is produced as an endproduct …

[HTML][HTML] Diversity and distribution of sulfur metabolic genes in the human gut microbiome and their association with colorectal cancer

PG Wolf, ES Cowley, A Breister, S Matatov, L Lucio… - Microbiome, 2022 - Springer
Background Recent evidence implicates microbial sulfidogenesis as a potential trigger of
colorectal cancer (CRC), highlighting the need for comprehensive knowledge of sulfur …

The 'in vivo lifestyle' of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial …

JM Ridlon, S Devendran, JM Alves, H Doden… - Gut …, 2020 - Taylor & Francis
The formation of secondary bile acids by gut microbes is a current topic of considerable
biomedical interest. However, a detailed understanding of the biology of anaerobic bacteria …

Table grape consumption reduces adiposity and markers of hepatic lipogenesis and alters gut microbiota in butter fat-fed mice

J Baldwin, B Collins, PG Wolf, K Martinez… - The Journal of nutritional …, 2016 - Elsevier
Our objective was to determine if consuming table grapes reduces adiposity and its
metabolic consequences and alters gut microbiota in mice fed a high-fat (HF), butter-rich …

Quercetin Alleviates Intestinal Oxidative Damage Induced by H2O2 via Modulation of GSH: In Vitro Screening and In Vivo Evaluation in a Colitis Model of Mice

Y Dong, Q Hou, J Lei, PG Wolf, H Ayansola… - ACS omega, 2020 - ACS Publications
The gastrointestinal tract is exposed to pro-oxidants from food, host immune factors, and
microbial pathogens, which may induce oxidative damage. Oxidative stress has been shown …

Introducing the microbes and social equity working group: considering the microbial components of social, environmental, and health justice

SL Ishaq, FJ Parada, PG Wolf, CY Bonilla, MA Carney… - …, 2021 - Am Soc Microbiol
Humans are inextricably linked to each other and our natural world, and microorganisms lie
at the nexus of those interactions. Microorganisms form genetically flexible, taxonomically …