The oral microbiota in colorectal cancer is distinctive and predictive
Background and aims Microbiota alterations are linked with colorectal cancer (CRC) and
notably higher abundance of putative oral bacteria on colonic tumours. However, it is not …
notably higher abundance of putative oral bacteria on colonic tumours. However, it is not …
[HTML][HTML] Exploratory analysis of covariation of microbiota-derived vitamin K and cognition in older adults
Background Vitamin K has multiple important physiological roles, including blood coagulation
and beneficial effects on myelin integrity in the brain. Some intestinal microbes possess …
and beneficial effects on myelin integrity in the brain. Some intestinal microbes possess …
[HTML][HTML] Helicobacter pylori motility
WO Paul, MC Lane, S Porwollik - Microbes and infection, 2000 - Elsevier
Motility is essential for Helicobacter pylori colonization. This review discusses the
biochemistry, genetics and genomics of the H. pylori flagellum, and compares these features …
biochemistry, genetics and genomics of the H. pylori flagellum, and compares these features …
Prevalence of malnutrition using harmonized definitions in older adults from different settings–A MaNuEL study
…, M O'Keeffe, M Kelly, E O'Herlihy, PW O'Toole… - Clinical nutrition, 2019 - Elsevier
Background & aims Malnutrition is widespread among older people and related to poor
outcome. Reported prevalences vary widely, also because of different diagnostic criteria used. …
outcome. Reported prevalences vary widely, also because of different diagnostic criteria used. …
Randomised study of endoscopic biliary endoprosthesis versus duct clearance for bileduct stones in high-risk patients
KB Chopra, RA Peters, PA O'Toole, SGJ Williams… - The Lancet, 1996 - thelancet.com
Background The value of an endoprosthesis for long-term management of bileduct stones
has not been formally established. The main theoretical advantage of endoprosthesis …
has not been formally established. The main theoretical advantage of endoprosthesis …
[HTML][HTML] Toward an improved definition of a healthy microbiome for healthy aging
The gut microbiome is a modifier of disease risk because it interacts with nutrition, metabolism,
immunity and infection. Aging-related health loss has been correlated with transition to …
immunity and infection. Aging-related health loss has been correlated with transition to …
[HTML][HTML] Whole blueberry and isolated polyphenol-rich fractions modulate specific gut microbes in an in vitro colon model and in a pilot study in human consumers
…, MC Neto, A Howell, A Thalacker-Mercer, PW O'Toole - Nutrients, 2020 - mdpi.com
Blueberry (BB) consumption is linked to improved health. The bioconversion of the polyphenolic
content of BB by fermentative bacteria in the large intestine may be a necessary step for …
content of BB by fermentative bacteria in the large intestine may be a necessary step for …
Non‐motile mutants of Helicobacter pylori and Helicobacter mustelae defective in flagellar hook production
PW O'Toole, M Kostrzynska, TJ Trust - Molecular microbiology, 1994 - Wiley Online Library
Flagellar hooks were purified from Helicobacter pylori and Helicobacter mustelae. The 70 ×
16nm H. pylori hook was composed of FIgE subunits of 78kDa, while the 72 × 16nm H. …
16nm H. pylori hook was composed of FIgE subunits of 78kDa, while the 72 × 16nm H. …
[HTML][HTML] Effect of room temperature transport vials on DNA quality and phylogenetic composition of faecal microbiota of elderly adults and infants
Background Alterations in intestinal microbiota have been correlated with a growing number
of diseases. Investigating the faecal microbiota is widely used as a non-invasive and …
of diseases. Investigating the faecal microbiota is widely used as a non-invasive and …
Microbiome alterations in IBS
We commend the editors of Gut for publishing the article by Hugerth et al 1 given that negative
results are conspicuously missing from the microbiome literature. The paper reports that …
results are conspicuously missing from the microbiome literature. The paper reports that …