The association between alcohol intake and alcoholic liver disease has been well
documented, although cirrhosis of the liver develops in only a small proportion of heavy …

Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …

Alcoholic liver disease (ALD) is a complex process that includes a wide spectrum of hepatic
lesions, from steatosis to cirrhosis. Cell injury, inflammation, oxidative stress, regeneration …

Background Single-agent nivolumab showed durable responses, manageable safety, and
promising survival in patients with advanced hepatocellular carcinoma in the phase 1–2 …

Background A 6-month abstinence from alcohol is usually required before patients with
severe alcoholic hepatitis are considered for liver transplantation. Patients whose hepatitis is …

Background Non-alcoholic steatohepatitis (NASH) is a common type of chronic liver disease
that can lead to cirrhosis. Obeticholic acid, a farnesoid X receptor agonist, has been shown …

Early identification of patients with severe (discriminant function≥ 32) alcoholic hepatitis
(AH) not responding to corticosteroids is crucial. We generated a specific prognostic model …

Background & Aims The effects of bariatric surgery in patients with nonalcoholic fatty liver
disease (NASH) are not well established. We performed a prospective study to determine …

The aims of this study were to evaluate the benefits of higher doses or of longer duration in
comparison with a standard interferon regimen (3 MU three times per week for 6 months) in …

BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) is a prevalent liver disease
associated with increased morbidity and mortality. Ursodeoxycholic acid (UDCA) may have …