The etiology of Parkinson's disease (PD) is multifactorial, with genetics, aging, and
environmental agents all a part of the PD pathogenesis. Widespread aggregation of the α …

Objective Intestinal inflammation has been suggested to play a role in development of
Parkinson's disease (PD) and multiple system atrophy (MSA). To test the hypothesis that IBD …

Alpha-synucleinopathies include Parkinson's disease, dementia with Lewy bodies, pure
autonomic failure and multiple system atrophy. These are all progressive neurodegenerative …

Aggregation of α‐synuclein is a hallmark of Parkinson's disease and dementia with Lewy
bodies. We here investigate the relationship between cytosolic Ca2+ and α‐synuclein …

Abstract Evaluation of gene expression levels by reverse transcription quantitative real-time
PCR (RT-qPCR) has for many years been the favourite approach for discovering disease …

Background The etiology of the neurogenerative disease multiple sclerosis (MS) is
unknown. The leading hypotheses suggest that MS is the result of exposure of genetically …

Wnt pathway is involved in synaptic plasticity and neuronal survival, and alterations in Wnt
signaling have previously been reported both in aging and neurodegenerative diseases …

Familial Parkinson disease (PD) is associated with rare genetic mutations, but the etiology in
most patients with sporadic (s) PD is largely unknown, and the basis for its progression to …

Multiple sclerosis (MS) is considered to be an autoimmune disease with an unknown cause
and with immune system dysregulation. Among environmental factors, viruses are most …

Total numbers of neurons, oligodendrocytes, astrocytes, and microglia in the basal ganglia
and red nucleus were estimated in brains from 11 patients with multiple system atrophy …