Although faecal microbiota transplantation (FMT) has a well-established role in the treatment
of recurrent Clostridioides difficile infection (CDI), its widespread dissemination is limited by …

Faecal microbiota transplantation (FMT) is an important therapeutic option for Clostridium
difficile infection. Promising findings suggest that FMT may play a role also in the …

Patients with Crohn's disease often develop perianal disease, successfully managed in most
cases. However, its most aggressive form, complex perianal disease, is associated with high …

Background Ciclosporin and infliximab are potential rescue treatments to avoid colectomy in
patients with acute severe ulcerative colitis refractory to intravenous corticosteroids. We …

Background & Aims Therapies for perianal fistulas in patients with Crohn's disease are often
ineffective in producing long-term healing. We performed a randomized placebo-controlled …

The use of Janus kinase (JAK) inhibitors is a new approach in the therapy of inflammatory
diseases with immune base. Tofacitinib is one of these inhibitors targeting JAK1 and JAK3 …

Background & Aims A small placebo-controlled trial reported the efficacy of mercaptopurine
therapy for children newly diagnosed with Crohn's disease, yet little is known about the …

Objective Ciclosporin and infliximab have demonstrated short-term similar efficacy as
second-line therapies in patients with acute severe UC (ASUC) refractory to intravenous …

Background and aims While it is commonly accepted that Inflammatory bowel disease (IBD)
Comprehensive Care Units (ICCUs) facilitate the delivery of quality care to Crohn's disease …

Cytomegalovirus (CMV) infection is common in humans. The virus then enters a “latency
phase” and can reactivate to different stimuli such as immunosuppression. The clinical …