Ulcerative colitis (UC) is a common gastrointestinal disorder in adults. Recent advances in
pathophysiology, immunology, and pharmaceutical science have resulted in a large number …

Crohn's disease (CD) is a chronic progressive destructive disease. Currently available
instruments measure disease activity at a specific point in time. An instrument to measure …

Mucosal healing (MH) has emerged as an important treatment goal for patients with IBD.
Historically, the therapeutic goals of induction and maintenance of clinical remission …

Background Reports of an increased risk of lymphoproliferative disorders in patients
receiving thiopurines for inflammatory bowel disease are controversial. We assessed this …

Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …

This second section of the European Crohn's and Colitis Organisation (ECCO) Consensus
on the management of Crohn's disease concerns treatment of active disease, maintenance …

BACKGROUND & AIMS: Patients with inflammatory bowel disease (IBD) who have been
exposed to thiopurines might have an increased risk of skin cancer. We assessed this risk …

Background Variability in endoscopic assessment necessitates rigorous investigation of
descriptors for scoring severity of ulcerative colitis (UC). Objective To evaluate variation in …

Background Ciclosporin and infliximab are potential rescue treatments to avoid colectomy in
patients with acute severe ulcerative colitis refractory to intravenous corticosteroids. We …

The advent of biological therapy has revolutionized inflammatory bowel disease (IBD) care.
Nonetheless, not all patients require biological therapy. Selection of patients depends on …