User profiles for "author:Philippe Seksik"

Philippe Seksik

PU-PH UPMC
Verified email at sat.aphp.fr
Cited by 29308

Analysis of bacterial bowel communities of IBD patients: what has it revealed?

H Sokol, C Lay, P Seksik… - Inflammatory bowel …, 2008 - academic.oup.com
The bacterial community, in whole or in part, resident in the bowel of humans is considered
to fuel the chronic immune inflammatory conditions characteristic of Crohn's disease and …

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

H Sokol, B Pigneur, L Watterlot… - Proceedings of the …, 2008 - National Acad Sciences
A decrease in the abundance and biodiversity of intestinal bacteria within the dominant
phylum Firmicutes has been observed repeatedly in Crohn disease (CD) patients. In this …

The intestinal microbiota in inflammatory bowel diseases: time to connect with the host

H Sokol, P Seksik - Current opinion in gastroenterology, 2010 - journals.lww.com
The intestinal microbiota in inflammatory bowel diseases: ti... : Current Opinion in
Gastroenterology The intestinal microbiota in inflammatory bowel diseases: time to connect …

Epidemiology and natural history of inflammatory bowel diseases

J Cosnes, C Gower–Rousseau, P Seksik, A Cortot - Gastroenterology, 2011 - Elsevier
In the West, the incidence and prevalence of inflammatory bowel diseases has increased in
the past 50 years, up to 8–14/100,000 and 120–200/100,000 persons, respectively, for …

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

B Lamas, ML Richard, V Leducq, HP Pham… - Nature medicine, 2016 - nature.com
Complex interactions between the host and the gut microbiota govern intestinal homeostasis
but remain poorly understood. Here we reveal a relationship between gut microbiota and …

Fungal microbiota dysbiosis in IBD

H Sokol, V Leducq, H Aschard, HP Pham, S Jegou… - Gut, 2017 - gut.bmj.com
Objective The bacterial intestinal microbiota plays major roles in human physiology and
IBDs. Although some data suggest a role of the fungal microbiota in IBD pathogenesis, the …

Tolerance of probiotics and prebiotics

P Marteau, P Seksik - Journal of clinical gastroenterology, 2004 - journals.lww.com
The clinical efficacy of probiotics and prebiotics has been proved in several clinical settings.
The authors review their proved or potential side effects. Probiotics as living microorganisms …

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

H Duboc, S Rajca, D Rainteau, D Benarous… - Gut, 2013 - gut.bmj.com
Objective Gut microbiota metabolises bile acids (BA). As dysbiosis has been reported in
inflammatory bowel diseases (IBD), we aim to investigate the impact of IBD-associated …

Predictors of Crohn's disease

L Beaugerie, P Seksik, I Nion–Larmurier, JP Gendre… - Gastroenterology, 2006 - Elsevier
Background & Aims: Early intensive therapy in Crohn's disease should be considered only
in patients with disabling disease. The aim of our study was to identify at diagnosis factors …

Specificities of the fecal microbiota in inflammatory bowel disease

H Sokol, P Seksik, L Rigottier-Gois… - Inflammatory bowel …, 2006 - academic.oup.com
Background Abnormalities have been described in the fecal microbiota of patients with IBD,
but it is not known whether they are specific for inflammatory bowel disease (IBD) or to some …