GUT Recent advances in basic science

Regulatory T-cell therapy in Crohn’s disease: challenges and advances
Jennie N Clough, Omer S Omer, Scott Tasker, Graham M Lord, Peter M Irving

Gut May 2020, 69 (5) 942-952; DOI: 10.1136/gutjnl-2019-319850
Non-coding RNAs in GI cancers: from cancer hallmarks to clinical utility
Mihnea Paul Dragomir, Scott Kopetz, Jaffer A Ajani, George Adrian Calin

Gut Apr 2020, 69 (4) 748-763; DOI: 10.1136/gutjnl-2019-318279
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells
Nick Powell, Eirini Pantazi, Polychronis Pavlidis, Anastasia Tsakmaki, Katherine Li, Feifei Yang, Aimee Parker, Carmen Pin, Domenico Cozzetto, Danielle Minns, Emilie Stolarczyk, Svetlana Saveljeva, Rami Mohamed, Paul Lavender, Behdad Afzali, Jonathan Digby-Bell, Tsui Tjir-Li, Arthur Kaser, Joshua Friedman, Thomas T MacDonald, Gavin A Bewick, Graham M Lord

Gut Mar 2020, 69 (3) 578-590; DOI: 10.1136/gutjnl-2019-318483
Liver organoids: from basic research to therapeutic applications
Nicole Prior, Patricia Inacio, Meritxell Huch

Gut Dec 2019, 68 (12) 2228-2237; DOI: 10.1136/gutjnl-2019-319256
miRNAs and NAFLD: from pathophysiology to therapy
Monika Gjorgjieva, Cyril Sobolewski, Dobrochna Dolicka, Marta Correia de Sousa, Michelangelo Foti

Gut Nov 2019, 68 (11) 2065-2079; DOI: 10.1136/gutjnl-2018-318146
JAK selectivity for inflammatory bowel disease treatment: does it clinically matter?
Silvio Danese, Marjorie Argollo, Catherine Le Berre, Laurent Peyrin-Biroulet

Gut Oct 2019, 68 (10) 1893-1899; DOI: 10.1136/gutjnl-2019-318448
Immune cell trafficking and retention in inflammatory bowel disease: mechanistic insights and therapeutic advances
Sebastian Zundler, Emily Becker, Lisa Lou Schulze, Markus F Neurath

Gut Sep 2019, 68 (9) 1688-1700; DOI: 10.1136/gutjnl-2018-317977
Leaky gut: mechanisms, measurement and clinical implications in humans
Michael Camilleri

Gut Aug 2019, 68 (8) 1516-1526; DOI: 10.1136/gutjnl-2019-318427
Messenger RNA therapy for rare genetic metabolic diseases
Pedro Berraondo, Paolo G V Martini, Matias A Avila, Antonio Fontanellas

Gut Jul 2019, 68 (7) 1323-1330; DOI: 10.1136/gutjnl-2019-318269
Role of the microbiome in human development
Maria Gloria Dominguez-Bello, Filipa Godoy-Vitorino, Rob Knight, Martin J Blaser

Gut Jun 2019, 68 (6) 1108-1114; DOI: 10.1136/gutjnl-2018-317503

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