Gut

Hepatic p63 regulates glucose metabolism by repressing SIRT1
Maria J Gonzalez-Rellan, Eva Novoa, Natalia da Silva Lima, Amaia Rodriguez, Christelle Veyrat-Durebex, Samuel Seoane, Begoña Porteiro, Marcos F Fondevila, Uxia Fernandez, Marta Varela-Rey, Ana Senra, Cristina Iglesias, Adriana Escudero, Miguel Fidalgo, Diana Guallar, Roman Perez-Fernandez, Vincent Prevot, Markus Schwaninger, Miguel López, Carlos Dieguez, Roberto Coppari, Gema Frühbeck, Ruben Nogueiras

Gut May 2022, gutjnl-2021-326620; DOI: 10.1136/gutjnl-2021-326620
Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model
Reinier G S Meester, Hilliene J van de Schootbrugge-Vandermeer, Emilie C H Breekveldt, Lucie de Jonge, Esther Toes-Zoutendijk, Arthur Kooyker, Daan Nieboer, Christian R Ramakers, Manon C W Spaander, Anneke J van Vuuren, Ernst J Kuipers, Folkert J van Kemenade, Iris D Nagtegaal, Evelien Dekker, Monique E van Leerdam, Iris Lansdorp-Vogelaar

Gut May 2022, gutjnl-2022-327188; DOI: 10.1136/gutjnl-2022-327188
Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett’s oesophagus and provides insights into clinical heterogeneity in reflux diagnosis
Jue-Sheng Ong, Jiyuan An, Xikun Han, Matthew H Law, Priyanka Nandakumar, 23andMe Research team, Esophageal cancer consortium, Johannes Schumacher, Ines Gockel, Anne Bohmer, Janusz Jankowski, Claire Palles, Catherine M Olsen, Rachel E Neale, Rebecca Fitzgerald, Aaron P Thrift, Thomas L Vaughan, Matthew F Buas, David A Hinds, Puya Gharahkhani, Bradley J Kendall, Stuart MacGregor

Gut Jun 2022, 71 (6) 1053-1061; DOI: 10.1136/gutjnl-2020-323906
Polyps and skin lesions: what could it be?
Tarek Nammour, Lamiaa Hamie, Kassem A Barada

Gut Jun 2022, 71 (6) 1061-1116; DOI: 10.1136/gutjnl-2021-324052
Chief cell plasticity is the origin of metaplasia following acute injury in the stomach mucosa
Brianna Caldwell, Anne R Meyer, Jared A Weis, Amy C Engevik, Eunyoung Choi

Gut Jun 2022, 71 (6) 1068-1077; DOI: 10.1136/gutjnl-2021-325310
Two waves of coeliac disease incidence in Sweden: a nationwide population-based cohort study from 1990 to 2015
David Bergman, James King, Benjamin Lebwohl, Mark S Clements, Bjorn Roelstraete, Gilaad G Kaplan, Peter HR Green, Joseph A Murray, Jonas F Ludvigsson

Gut Jun 2022, 71 (6) 1088-1094; DOI: 10.1136/gutjnl-2021-324209
Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events
Siew C Ng, Ye Peng, Lin Zhang, Chris KP Mok, Shilin Zhao, Amy Li, Jessica YL Ching, Yingzhi Liu, Shuai Yan, Dream L S Chan, Jie Zhu, Chunke Chen, Adrian CH Fung, Kenneth KY Wong, David SC Hui, Francis KL Chan, Hein M Tun

Gut Jun 2022, 71 (6) 1106-1116; DOI: 10.1136/gutjnl-2021-326563
Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium
Lochlan Fennell, Alexandra Kane, Cheng Liu, Diane McKeone, Gunter Hartel, Chang Su, Catherine Bond, Mark Bettington, Barbara Leggett, Vicki Whitehall

Gut Jun 2022, 71 (6) 1127-1140; DOI: 10.1136/gutjnl-2020-322166
Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures
Maria Arechederra, María Rullán, Irene Amat, Daniel Oyon, Lucia Zabalza, Maria Elizalde, M Ujue Latasa, Maria R Mercado, David Ruiz-Clavijo, Cristina Saldaña, Ignacio Fernández-Urién, Juan Carrascosa, Vanesa Jusué, David Guerrero-Setas, Cruz Zazpe, Iranzu González-Borja, Bruno Sangro, Jose M Herranz, Ana Purroy, Isabel Gil, Leonard J Nelson, Juan J Vila, Marcin Krawczyk, Krzysztof Zieniewicz, Waldemar Patkowski, Piotr Milkiewicz, Francisco Javier Cubero, Gorka Alkorta-Aranburu, Maite G Fernandez-Barrena, Jesus M Urman, Carmen Berasain, Matias A Avila

Gut Jun 2022, 71 (6) 1141-1151; DOI: 10.1136/gutjnl-2021-325178
Long-term yield of pancreatic cancer surveillance in high-risk individuals
Kasper A Overbeek, Iris J M Levink, Brechtje D M Koopmann, Femme Harinck, Ingrid C A W Konings, Margreet G E M Ausems, Anja Wagner, Paul Fockens, Casper H van Eijck, Bas Groot Koerkamp, Olivier R C Busch, Marc G Besselink, Barbara A J Bastiaansen, Lydi M J W van Driel, Nicole S Erler, Frank P Vleggaar, Jan-Werner Poley, Djuna L Cahen, Jeanin E van Hooft, Marco J Bruno

Gut Jun 2022, 71 (6) 1152-1160; DOI: 10.1136/gutjnl-2020-323611

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