Absorption of radioactive vitamin B12 was measured by the Schilling procedure in 14 patients who had had a partial gastrectomy. Injection of carbachol (250 μg) before the administration of the test dose increased absorption to a much smaller degree than the ingestion of a light meal containing a minimal quantity of the natural vitamin. The results support the belief that food may improve absorption of vitamin B12 after partial gastrectomy by stimulating the secretion of a small residual amount of intrinsic factor.
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