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Hereditary angioneurotic oedema: an unusual case of recurring abdominal pain
  1. Edward J. Feller,
  2. Howard M. Spiro,
  3. Leonard A. Katz


    Two patients with hereditary angioneurotic oedema, a condition characterized by repeated episodes of abdominal pain and oedema, and by an absence of complement-1 esterase inhibitor activity in the plasma are presented in detail. Both underwent multiple surgical procedures before the diagnosis was established. Abdominal pain is often the presenting complaint, and although a complete history will usually lead to the proper diagnosis, cases in which the family history is not clear can present a diagnostic dilemma. Characteristic radiological demonstration of localized intestinal oedema will only be obtained if studies are performed early during the acute attack.

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    • 1 Requests for reprints should be addressed to: Howard M. Spiro, 333 Cedar Street, New Haven, Conn., 06510, USA.