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Abnormal metabolism of secondary bile acids in patients with cirrhosis
  1. Z. R. Vlahcevic,
  2. I. Buhac,
  3. C. C. Bell, Jr,
  4. Leon Swell


    The composition of bile acids in human bile was determined in bile-rich duodenal fluid on four consecutive days in a group of seven patients with cirrhosis and eight control patients with no liver disease. There was a marked reduction of secondary biliary bile acids in cirrhotic patients. Possible mechanisms for these changes are discussed.

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    • 1 Requests for reprints should be sent to Dr Z. R. Vlahcevic, Gastroenterology Section, McGuire Veterans Administration Hospital, Richmond, Virginia 23219, USA.